Antidepressants during pregnancy: are they recommended?

Taking medicines during pregnancy carries risks and benefits. Inform yourself about what it means to take antidepressants during pregnancy.

Antidepressants during pregnancy

According to a report by Mayo Clinic staff in Kenya, antidepressants are the primary treatment option for most types of depression. However, the benefits and risks of taking antidepressants during pregnancy should be taken into account. We cleared up some important doubts you need to know.

Antidepressants during pregnancy: are they recommended?

Why it is important to treat depression during pregnancy

If you are pregnant and are going through a period of depression, it is very important that you deal with specialized professionals.otherwise, you may not be looking for the best prenatal care or eating the healthy foods that both you and your baby need.

There is a link between greater depression during pregnancy and increased risk of premature birth, low birth weight, lower fetal growth, and other newborn disorders

Instability of depression during pregnancy also increases the risk of postpartum depression, early termination of breastfeeding, and difficulty establishing a link with the baby.

Antidepressants: are they an option during pregnancy?

The decision to use antidepressants during pregnancy is based on a balance between risks and benefits. Few medications have been proven safe during pregnancy and certain types of antidepressants have been associated with complications for infants.

If you take antidepressants during pregnancy, your doctor will try to minimize your baby’s exposure to the medication. This is achieved with monotherapy, that is to say, it prescribes only one medicine at the lowest dose that takes effect, especially during the first trimester.

Antidepressants: are they an option during pregnancy?

What antidepressants may be taken during pregnancy

Antidepressant options during pregnancy are usually the following::

Selective serotonin reuptake inhibitors (SSRIs))

During pregnancy, selective serotonin reuptake inhibitors, including cytalopram (Celexa), fluoxetine (Prozac) and sertraline (Zoloft), are considered an option. Possible complications include increased risk of severe bleeding after delivery (postpartum hemorrhage), premature delivery, and low birth weight. Most studies show that selective serotonin reuptake inhibitors are not related to birth defects.; however, paroxetine (Paxil) does appear to be associated with a slightly higher risk of congenital heart defects in the foetus.

Serotonin and norepinephrine reuptake inhibitors (IRSN))

These inhibitors are also considered an option during pregnancy and include Duloxetine (Cymbalta) and venlafaxine (Effexor XR).

However, studies suggest a relationship between taking serotonin re uptake inhibitors and norepinephrine at the end of pregnancy and postpartum haemorrhage.

Serotonin and norepinephrine reuptake inhibitors (IRSN))

Bupropion (Wellbutrin)

This medicine is used both to treat depression and to stop smoking. While bupropion is not generally considered a first-line treatment for depression during pregnancy, it may be an option for women who did not respond to other medications.

Several studies suggest that there may be a relationship between taking bupropion during pregnancy and heart defects.

Tricyclic antidepressants

Nortriptyline (Pamelor) is one of these medicines. Although tricyclic antidepressants are not generally considered as first-or second-line treatment, they may be an option for women who have not responded to other medications.

The tricyclic antidepressant clomipramine may be associated with birth defects in the foetus, including heart defects. The use of these medications during the second or third trimester may also be linked to postpartum hemorrhage.


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